GTx-TRANSPORTER

Os testes genéticos revolucionaram a medicina personalizada, permitindo que profissionais de saúde compreendam melhor a constituição genética de um paciente e seu potencial impacto nas respostas a medicamentos. Uma área de interesse são os genes de transporte de medicamentos, que desempenham um papel crucial na absorção, distribuição, metabolismo e excreção de medicamentos no corpo. O GTx-Transportador pode fornecer informações valiosas sobre o metabolismo de medicamentos de um paciente e sua possível resposta a determinados medicamentos.

SOLUTIONS

Software tools, panels, exclusive pipelines and more, everything you need for mining and interpreting biological data. Accurate, complete, and sophisticated bioinformatics services to drive your tests, discovery and maximize your ROI.

Precision Medicine

In the realm of healthcare, Precision Medicine emerges as a revolutionary approach that tailors medical treatments to individual patients based on their unique genetic makeup. By harnessing cutting-edge technologies and comprehensive data analysis, Precision Medicine ushers in a new era of personalized healthcare, offering the potential to improve patient outcomes, enhance disease prevention, and optimize therapeutic strategies.

As Precision Medicine continues to advance, its impact on healthcare is poised to be transformative. By harnessing the power of personalized data-driven insights, this groundbreaking approach has the potential to reshape the medical landscape, leading to an era of more precise, effective, and patient-centric healthcare that holds the promise of improved outcomes and enhanced well-being for individuals worldwide.

GTx Onco™

GTx-Onco is a computational tool for the interpretation of cancer genome data (large gene panels, WES and/or WGS). GTx-Onco provides actionable recommendations, linked to therapeutic and nutritional aspects, based on the genetic profile of the tumor.

GTx - 500

GTx-500 is a NGS-based assay that enable a genomic profiling of the tumor by sequencing a panel of >500 cancer genes. Furthermore, the assay allows the calculation of two important immunological parameters: MSI (microsatellite instability) and TMB (tumor mutational burden).

Environmental & Agricultural

Omics technologies and agriculture converge to unlock a new era of sustainable and efficient farming practices. By harnessing the power of genetic information, farmers and researchers are redefining the way we cultivate crops and raise livestock. With DNA GTx Bioinformatics solutions as their ally, farmers are poised to cultivate a resilient and prosperous agricultural landscape, meeting the demands of a rapidly evolving world.

At the same pace, omics technologies are revolutionizing our approach to environmental conservation, ecological restoration, and sustainable resource management. DNA GTx Bioinformatics solutions in genomics, metagenomics and meta-barcoding empower scientists and companies to uncover crucial insights into the intricate workings of ecosystems. DNA GTx Bioinformatics is poised to forge a harmonious relationship between humanity and the natural world, ensuring a thriving and resilient planet for future generations.

GTx Proteo™

GTx Proteo is a computational tool for proteogenomics. Our know-how in the analysis of MS/MS data allowed us to develop a platform for the integration of proteomic, transcriptomic and genomic data.

GTx - Meta

GTx-Meta is a pipeline for the analysis of metagenomics data, both 16S/18S or shotgun libraries. It takes FASTQ files as input and generates BAM files as products. Furthermore, GTx-Meta produces a detailed report with several downstream analyses, adapted to either a taxonomic or functional approach.
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GTx - Barcode

Metabarcoding is the large-scale taxonomic identification of complex environmental samples through the sequencing of one or few genes (usually present in the mitochondrial genome). GTx-Barcode is a pipeline for the analysis of metabarcoding data.

GTx - Pipeline

DNA GTx Pipeline is a pipeline framework and process manager that allows an optimization of the computations demands in a given project with a reduction in costs and time. Some functionalities include: parallelization, automatic check of process status and an interface for the management of processes.

O que é o GTx-Transportador?

O GTx-Transportador é um tipo de teste genético que analisa mais de 40 genes envolvidos nos processos de transporte de medicamentos. Esses genes codificam proteínas responsáveis por transportar medicamentos e seus metabólitos através das membranas celulares, principalmente em órgãos como o fígado, rins, intestinos e barreira hematoencefálica. Ao identificar variações genéticas (polimorfismos) nesses genes, os profissionais de saúde podem prever a capacidade de transporte de medicamentos de um indivíduo, o que pode influenciar sua resposta aos medicamentos e sua susceptibilidade a reações adversas.

Next Generation Sequencing (NGS) Analysis

Our team includes pioneers in NGS analysis. We offer processing and analysis services for various technologies, including variant calling and visualization (D-KRYPT), RNA-Seq (DNA GTx RNA), metagenomics and others (consult us).

GTx - RNA

GTx-Onco is a computational tool for the interpretation of cancer genome data (large gene panels, WES and/or WGS). GTx-Onco provides actionable recommendations, linked to therapeutic and nutritional aspects, based on the genetic profile of the tumor.
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Genome Assembly

DNA-GTx Bioinformatics "Genome Assembly and Annotation Service" is a cutting-edge bioinformatics service designed to assist researchers, geneticists, and biologists in analyzing and understanding the complex structure and function of genomes. This service combines advanced computational algorithms and expertise to assemble and annotate genomes, providing valuable insights into genetic composition, gene identification, regulatory elements, and other functional elements.
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GTx-Population

Unlock the secrets of human diversity and evolutionary history with GTx-Population, the cutting-edge bioinformatics service tailored for populational genomics. Delve deep into the genetic tapestry of populations and unearth invaluable insights into their unique genetic makeup, disease associations, migratory patterns, and ancestral origins.

Aplicações Clínicas:

As informações obtidas a partir do GTx-Transportador podem ser úteis em várias situações clínicas:

Seleção de Medicamentos: Identificação de medicamentos que provavelmente serão bem tolerados e eficazes com base no perfil genético do paciente.

Dosagem de Medicamentos: Otimização das dosagens de medicamentos para alcançar o efeito terapêutico desejado, ao mesmo tempo em que se minimizam reações adversas.

Prevenção de Reações Adversas: Identificação de medicamentos que possam apresentar um risco aumentado de reações adversas no paciente e evitar seu uso sempre que possível.

Interações Medicamentosas: Previsão de possíveis interações medicamentosas para evitar combinações prejudiciais.

Planos de Tratamento Personalizados: Elaboração de planos de tratamento personalizados com base em variações genéticas individuais.

Limitações:

O GTx-Transportador fornece informações valiosas, mas é apenas uma peça do quebra-cabeça na determinação das respostas aos medicamentos. Outros fatores, como estilo de vida, dieta e outros medicamentos sendo tomados, também podem desempenhar um papel importante. Nem todas as interações medicamentosas-genéticas são completamente compreendidas, portanto, a interpretação de algumas variantes genéticas pode ser incerta ou requerer mais pesquisas. Considerações éticas e de privacidade relacionadas aos testes genéticos devem ser abordadas, garantindo o consentimento do paciente e a proteção dos dados.

Conclusão:

O GTx-Transportador é uma ferramenta poderosa no campo da medicina personalizada, permitindo que os profissionais de saúde tomem decisões mais informadas sobre a seleção de medicamentos, dosagem e potenciais interações. Ao considerar a constituição genética de um paciente, os profissionais médicos podem otimizar as terapias medicamentosas, resultando em melhores resultados de tratamento e maior segurança para o paciente. No entanto, é importante combinar as informações genéticas com outros fatores clínicos para tomar decisões abrangentes no cuidado ao paciente.

Customized

DNA GTx Bioinformatics recognizes that each customer is unique, with distinct preferences, requirements, and aspirations. Gone are the days of one-size-fits-all approaches. Instead, businesses are leveraging advanced technologies, data analytics, and personalized insights to understand customers on a granular level. By offering tailored experiences, products, and solutions, DNA GTx Bioinformatics hopes to empower consumers and foster a deeper sense of satisfaction and loyalty. So, if you have a bioinformatics problem that needs to be addressed through innovative solutions, DNA GTx Bioinformatics can help you.

The amount of genomic data generated represents the revolution in biological and medical sciences established by new DNA sequencing technologies. In order to encompass the data complexity and the desirable access and analysis flexibility we have a PhD-level team to design and implement the solutions you need to improve your services and products capabilities by helping your clients and patients more satisfied.Our bioinformatics customization services are conducted in close contact and interaction with your team, focused on cost reduction, quality and quick responses.

  • To adopt a new and customized interface to monitor your data analysis pipeline;
  • To improve processes by making them faster, integrated, automated, and stable;
  • Achieve a superior level in Quality Control by adding and automatizing new checking points;
  • Add value to final analysis and reports by employing different methods and meeting new market demands;
  • Monitor the sample processing by tracking the whole flux with secure and updated interface, hosted in the cloud or on-premises.

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