GTx-500

O GTx-500 é um teste genético avançado projetado para analisar um conjunto abrangente de genes associados a vários tipos de câncer. Essa abordagem baseada em painel gênico permite a avaliação simultânea de vários genes, fornecendo informações valiosas sobre o risco de câncer de um indivíduo, opções de tratamento potenciais e prognóstico. O teste representa um avanço significativo no cuidado personalizado do câncer e auxilia os profissionais de saúde a tomar decisões mais informadas para a prevenção do câncer, detecção precoce e terapias direcionadas.

SOLUTIONS

Software tools, panels, exclusive pipelines and more, everything you need for mining and interpreting biological data. Accurate, complete, and sophisticated bioinformatics services to drive your tests, discovery and maximize your ROI.

Precision Medicine

In the realm of healthcare, Precision Medicine emerges as a revolutionary approach that tailors medical treatments to individual patients based on their unique genetic makeup. By harnessing cutting-edge technologies and comprehensive data analysis, Precision Medicine ushers in a new era of personalized healthcare, offering the potential to improve patient outcomes, enhance disease prevention, and optimize therapeutic strategies.

As Precision Medicine continues to advance, its impact on healthcare is poised to be transformative. By harnessing the power of personalized data-driven insights, this groundbreaking approach has the potential to reshape the medical landscape, leading to an era of more precise, effective, and patient-centric healthcare that holds the promise of improved outcomes and enhanced well-being for individuals worldwide.

GTx Onco™

GTx-Onco is a computational tool for the interpretation of cancer genome data (large gene panels, WES and/or WGS). GTx-Onco provides actionable recommendations, linked to therapeutic and nutritional aspects, based on the genetic profile of the tumor.

GTx - 500

GTx-500 is a NGS-based assay that enable a genomic profiling of the tumor by sequencing a panel of >500 cancer genes. Furthermore, the assay allows the calculation of two important immunological parameters: MSI (microsatellite instability) and TMB (tumor mutational burden).

Environmental & Agricultural

Omics technologies and agriculture converge to unlock a new era of sustainable and efficient farming practices. By harnessing the power of genetic information, farmers and researchers are redefining the way we cultivate crops and raise livestock. With DNA GTx Bioinformatics solutions as their ally, farmers are poised to cultivate a resilient and prosperous agricultural landscape, meeting the demands of a rapidly evolving world.

At the same pace, omics technologies are revolutionizing our approach to environmental conservation, ecological restoration, and sustainable resource management. DNA GTx Bioinformatics solutions in genomics, metagenomics and meta-barcoding empower scientists and companies to uncover crucial insights into the intricate workings of ecosystems. DNA GTx Bioinformatics is poised to forge a harmonious relationship between humanity and the natural world, ensuring a thriving and resilient planet for future generations.

GTx Proteo™

GTx Proteo is a computational tool for proteogenomics. Our know-how in the analysis of MS/MS data allowed us to develop a platform for the integration of proteomic, transcriptomic and genomic data.

GTx - Meta

GTx-Meta is a pipeline for the analysis of metagenomics data, both 16S/18S or shotgun libraries. It takes FASTQ files as input and generates BAM files as products. Furthermore, GTx-Meta produces a detailed report with several downstream analyses, adapted to either a taxonomic or functional approach.
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GTx - Barcode

Metabarcoding is the large-scale taxonomic identification of complex environmental samples through the sequencing of one or few genes (usually present in the mitochondrial genome). GTx-Barcode is a pipeline for the analysis of metabarcoding data.

GTx - Pipeline

DNA GTx Pipeline is a pipeline framework and process manager that allows an optimization of the computations demands in a given project with a reduction in costs and time. Some functionalities include: parallelization, automatic check of process status and an interface for the management of processes.

O que é o GTx-500 ?

O GTx-500 é uma análise genética de alto rendimento que se concentra em um conjunto específico de genes conhecidos por estarem ligados ao desenvolvimento e progressão de diferentes tipos de câncer. Ele utiliza a tecnologia de sequenciamento de segunda geração (NGS) para examinar as sequências de DNA desses genes, identificando variações genéticas ou mutações que podem ser relevantes para o risco de câncer e resposta ao tratamento.

Next Generation Sequencing (NGS) Analysis

Our team includes pioneers in NGS analysis. We offer processing and analysis services for various technologies, including variant calling and visualization (D-KRYPT), RNA-Seq (DNA GTx RNA), metagenomics and others (consult us).

GTx - RNA

GTx-Onco is a computational tool for the interpretation of cancer genome data (large gene panels, WES and/or WGS). GTx-Onco provides actionable recommendations, linked to therapeutic and nutritional aspects, based on the genetic profile of the tumor.
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Genome Assembly

DNA-GTx Bioinformatics "Genome Assembly and Annotation Service" is a cutting-edge bioinformatics service designed to assist researchers, geneticists, and biologists in analyzing and understanding the complex structure and function of genomes. This service combines advanced computational algorithms and expertise to assemble and annotate genomes, providing valuable insights into genetic composition, gene identification, regulatory elements, and other functional elements.
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GTx-Population

Unlock the secrets of human diversity and evolutionary history with GTx-Population, the cutting-edge bioinformatics service tailored for populational genomics. Delve deep into the genetic tapestry of populations and unearth invaluable insights into their unique genetic makeup, disease associations, migratory patterns, and ancestral origins.

Genes Analizados:

O GTx-500 examina uma ampla variedade de genes relacionados ao câncer, incluindo, mas não se limitando a:

Oncogenes: Genes que, quando mutados, promovem a proliferação celular e contribuem para o desenvolvimento do câncer.

Genes Supressores de Tumor: Genes que, quando funcionam adequadamente, ajudam a regular o crescimento celular e previnem o câncer.

Genes de Reparo do DNA: Genes envolvidos na manutenção da integridade do genoma e na reparação de danos no DNA, mutações nos quais podem aumentar o risco de câncer.

Genes Farmacogenômicos: Genes que influenciam como um indivíduo metaboliza e responde a medicamentos contra o câncer.

Esses genes abrangem diversos tipos de câncer, como câncer de mama, pulmão, cólon, próstata, ovário e outros.

Aplicações Clínicas:

O GTx-500 possui diversas aplicações clínicas, tais como:

Prevenção do Câncer: Identificar indivíduos com alto risco genético para tipos específicos de câncer permite a realização de triagens direcionadas e estratégias preventivas.

Diagnóstico Precoce: A detecção precoce de mutações relacionadas ao câncer auxilia no diagnóstico do câncer em seus estágios mais iniciais e tratáveis.

Seleção de Tratamento: As informações genéticas auxiliam os oncologistas a escolher as opções de tratamento mais eficazes e apropriadas para os pacientes individuais.

Previsão de Prognóstico: Marcadores genéticos podem fornecer informações sobre o provável desfecho da doença de um paciente e orientar o planejamento do tratamento.

Participação em Ensaios Clínicos: Identificação de pacientes elegíveis para terapias direcionadas e ensaios clínicos que exploram tratamentos inovadores.

Limitações:

Embora o GTx-500 forneça informações valiosas, nem todas as mutações genéticas têm uma significância clínica conhecida ou implicações claras de tratamento. Os testes genéticos podem revelar descobertas inesperadas (achados incidentais) não relacionadas ao risco de câncer, o que requer consideração cuidadosa e aconselhamento. O GTx-500 deve ser utilizado em conjunto com outras avaliações clínicas e diagnósticas para tomar decisões médicas bem fundamentadas.

Conclusão:

O GTx-500 é uma análise genética de ponta que oferece uma avaliação abrangente de genes relacionados ao câncer, fornecendo informações cruciais para a avaliação do risco de câncer, detecção precoce, seleção de tratamento e previsão de prognóstico. Ele representa um avanço significativo na medicina de precisão e ajuda a adaptar o cuidado do câncer aos pacientes individuais, melhorando, em última instância, os resultados e a qualidade de vida dos pacientes.

Customized

DNA GTx Bioinformatics recognizes that each customer is unique, with distinct preferences, requirements, and aspirations. Gone are the days of one-size-fits-all approaches. Instead, businesses are leveraging advanced technologies, data analytics, and personalized insights to understand customers on a granular level. By offering tailored experiences, products, and solutions, DNA GTx Bioinformatics hopes to empower consumers and foster a deeper sense of satisfaction and loyalty. So, if you have a bioinformatics problem that needs to be addressed through innovative solutions, DNA GTx Bioinformatics can help you.

The amount of genomic data generated represents the revolution in biological and medical sciences established by new DNA sequencing technologies. In order to encompass the data complexity and the desirable access and analysis flexibility we have a PhD-level team to design and implement the solutions you need to improve your services and products capabilities by helping your clients and patients more satisfied.Our bioinformatics customization services are conducted in close contact and interaction with your team, focused on cost reduction, quality and quick responses.

  • To adopt a new and customized interface to monitor your data analysis pipeline;
  • To improve processes by making them faster, integrated, automated, and stable;
  • Achieve a superior level in Quality Control by adding and automatizing new checking points;
  • Add value to final analysis and reports by employing different methods and meeting new market demands;
  • Monitor the sample processing by tracking the whole flux with secure and updated interface, hosted in the cloud or on-premises.

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